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Dangerous and Defective Products

11/17/2008
David M. Paul
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New Study Shows BPA may Interfere with Chemotherapy

A chemical widely used in hard plastic drinking bottles and the lining of food cans may reduce the effectiveness of chemotherapy treatment, a new study shows.

The findings, reported in the journal Environmental Health Perspectives adds to the growing list of concerns about bisphenol-a, or BPA, a chemical used to make the hard, clear and nearly unbreakable plastic called polycarbonate. The plastic is also found in the lining of nearly every soft drink and canned food product.

In the latest research, a team from the University of Cincinnati studied human breast cancer cells, subjecting them to low levels of BPA similar to those found in the blood of adults. They found that BPA acts on cancer cells similar to the way estrogen does — by inducing proteins that protect the cells from chemotherapy agents.

The research may help explain why chemotherapy appears to be less effective in some patients




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